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The trial is ongoing and will extend to 240 weeks to determine whether the histologic improvements observed at 72 weeks translate into reductions in mortality, liver transplant, and other major liver-related events

Standardized uptake value (SUV) was calculated [SUV = radioactivity activity concentration (KBq/ml)/body weight (g)/injected dose (kBq)] for semi-quantitative analysis

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10.1016/j.metabol.2013.09.009 Metabolism Summary Keywords T2DM (type 2 diabetes), GLP-1, -cell, PARP-1, ABCA1 Citation Li R, Sun X, Li P, Li W, Zhao L, Zhu L and Zhu S (2021) GLP-1-Induced AMPK Activation Inhibits PARP-1 and Promotes LXR-Mediated ABCA1 Expression to Protect Pancreatic -Cells Against Cholesterol-Induced Toxicity Through Cholesterol Efflux

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