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Patients using the medication as part of a comprehensive weight management program that includes a calorie-reduced diet and increased physical activity have experienced significant weight loss compared to those on a placebo
The DIO rats treated with a vehicle gained 5.0 +/- 1.0 grams during the experiment
Epub 2021 Jan 21
Compound-Specific Oncologic Effects As highlighted in this meta-analysis, no conclusive association between the use of GLP-1 RAs and an increase in gastrointestinal cancers has been established
McConnell added, "Not knowing the safety of the drug, I think [patients] should be cautious and try not to get pregnant while taking it because we don't know the long-term effects." Both doctors recommended the use of "backup barriers," or extra contraceptives, while taking GLP-1 drugs
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