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Public dataset and bioinformatics The GEO datasets were downloaded from NCBI (www.ncbi.nlm.nih.gov)
Emerging evidence indicates that riboflavin deficiency skews microglia toward a pro-inflammatory M1 phenotype, characterized by elevated iNOS, IL-1, and TNF-, whereas riboflavin supplementation promotes an anti-inflammatory M2 phenotype, with higher IL-10 and TGF- expression via STAT6 activation (67, 68)
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Reconstitution: Note: Always centrifuge the vial before opening
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