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Moreover, the bioavailability and absorption of antioxidants vary between individuals, which complicates dosage recommendations

58 Phase 2a trial of GSBR-1290 (120mg) in 40 healthy obese volunteers over 8 weeks demonstrated a significant reduction in BW (120 mg: -4.74%

Use caution with anticoagulant meds

However, real-life analyses indicate a higher discontinuation rate, of approximately 70% stopping within 2 years, especially in non-diabetic patients (112, 113)

doi: 10.1093/molehr/gaab067 87 XuanYWangHYungMMChenFChanWSChanYSet al