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This explains why the magnitude is smaller than retatrutide, which adds direct glucagon receptor-mediated cardiac effects on top of the indirect GLP-1 effects
(12) Macvanin M, Gluvic Z, Radovanovic J, Essack M, Gao X, Isenovic ER
Retatrutide is an investigational injectable peptide currently under clinical evaluation for the treatment of obesity and type 2 diabetes mellitus
Thompson, J., Diab, H., Datta, P., & Krutsch, K
If patients experience concerning or persistent injection site reactions, they should discuss these with their healthcare provider rather than assuming such reactions are too minor to report
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