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10.1371/journal.pone.0050117 51
But if you weight effectiveness as a function of risk/benefit, not just pigment density, the picture changes: a slightly milder tan produced by a more selective, clinically studied drug may be preferable to the dramatic but pharmacologically messy profile of Melanotan IIespecially when the latter is sourced from unregulated research chemical suppliers
It has been suggested that these entities share with BIN, DPN, and PEM the existence of a spectrum within the spectrum (43), namely: a set of atypical histopathological features which can be variously combined with each other, thereby bearing a spectrum of lesions with increasing risk of disease progression up to overtly malignant neoplasms
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