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Reach for solutions that work at the cellular level
These medications are effective early in their use, but lose efficacy due to the formation of systemic antibodies against them over time
For instance, a number of ongoing or completed trials are evaluating inhibitors of the PI3K-AKT-mTOR cascade, such as gedatolisib (NCT03065062) in advanced solid tumors, capivasertib (NCT04305496) in hormone receptor-positive breast cancer, and alpelisib (NCT02437318), which has shown efficacy in advanced breast cancer and is already approved for PIK3CA-mutated cases
However, because clinical trials on supplements in pregnant populations are limited, you should always consult your OB-GYN before starting a new routine
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