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reported a prevalence of 20.5% among Indian males.[] It is more common in Fitzpatrick skin types IV, V and VI namely the Hispanic, Caribbean and Asian races as they live in areas exposed to intense ultraviolet (UV) radiation resulting in larger amounts of melanin production.[] In India, melasma is the most common pigmentary disorder, with an incidence of approximately 10%;[] often developing at a younger age having strong correlation with positive family history, thus, supporting the role of genetic factors in its development.[] Although the exact pathogenesis is unknown, dysfunctional melanogenesis plays a pivotal role
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[28] Companies manufacturing skin lightening products take advantage of the lax advertising laws and make unsubstantiated claims about their efficacy taking a horrendous toll on the consumers
3.4.1 Protective effects of metformin on cardiovascular disease risk in patients with polycystic ovary syndrome Epidemiological research suggests that individuals with PCOS exhibit a greater prevalence of hypertension compared to those without PCOS, particularly among females of reproductive age, and their cardiovascular risk is notably elevated irrespective of their BMI
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