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Los pacientes diabticos con funcin renal y trabajadores fsicos y mentales, debido a que excretan muchos desechos y consumen una gran cantidad de L-carnitina en el cuerpo, pueden provocar fcilmente una deficiencia de L-carnitina y requerir suplementacin a largo plazo
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Zikopoulos B, Barbas H (2010) Changes in prefrontal axons may disrupt the network in autism
Inflammation and mitochondrial dysfunction: A vicious circle in neurodegenerative disorders
However, AD pathology extends beyond amyloid and tau, encompassing a multifaceted array of pathophysiological mechanisms, including chronic neuroinflammation, oxidative stress, mitochondrial dysfunction, impaired proteostasis (the homeostasis of protein folding, stability, and degradation), calcium dysregulation, excitotoxicity, and breakdown of the blood-brain barrier (BBB) [16, 17]
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