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Cancer considerations: Any compound promoting tissue growth raises theoretical questions about cancer
Furthermore, TB-500 seemingly reversed the action of DAPT and BMS, which may support its role in regulating these pathways
As discussed above, unlike Y37 rAmy , P37 Cagri does not interact directly with RAMP1 or RAMP3, which likely decreases the stability of the ECD interface, leading to increased dynamics relative to the rAmy-bound AMY 1 R and rAmy-bound AMY 3 R (Fig
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