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Ji LL, Dillon D, Wu E
Findings from recently completed trials indicate that a GLP-1 RA-induced increase in HR, regardless of magnitude, does not present an increased cardiovascular risk for subjects with T2DM, although a pronounced increase in HR may be associated with adverse clinical outcomes in those with advanced heart failure
For the surgical procedure, rats were anesthetized using ketamine (70 mg/kg, intramuscular (I.M.)) and xylazine (8 mg/kg, I.M.) (Salazar et al
Hashimoto K, et al
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