DSIP is under active research for potential application in: Individuals with insomnia or light, fragmented sleep Those with chronic stress or HPA axis dysfunction Athletes and biohackers seeking enhanced recovery People working night shifts or experiencing circadian misalignment Adults with low growth hormone output or reduced sleep efficiency Patients with PTSD or trauma-related sleep disruption (research ongoing) DSIP is not FDA-approved for any medical condition and should only be used in research settings under supervision
L-citrulline as a single supplementation appears to have yielded superior outcomes than L-arginine supplementation
GHK-Cu activates copper-dependent collagen synthesis and antioxidant gene expression
Interestingly, in a recent study using resistant colon cancer stem-like cells and mouse models, combination therapy of regorafenib with two antagonists of IGF-1-R, namely aspirin and the selective dual insulin receptor and IGF-1R kinase inhibitor linsitinib (OSI-906), abrogated tumor resistance to regorafenib and restored the drugs ability to induce apoptosis in colon cancer stem-like cells and disease activity index (51)
Pastore, A., Federici, G., Bertini, E