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In the SKOV-3 and CAOV-3 cell lines, Ex-4 induces the activation of caspase-3/7 (cas-3/7), leading to the inhibition of tumor cell migration and induction of apoptosis [78]
The lactulose excretion over 24 h (likely to represent only small intestinal permeability), subtracted from 24-h sucralose excretion, is considered to give an isolated measure of colonic permeability [134]
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