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Subsequent flow cytometric analysis of NRF2 expression in ILC2s revealed that melatonin treatment significantly increased NRF2 protein levels ( Figure 6D )

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Safety data were analysed descriptively by treatment group (oral semaglutide 3 mg, 7 mg, 14 mg, flexibly dosed, and comparators) and background medication/insulin regimen subgroup for all patients in the trials for the incidence of adverse events (AEs), including serious AEs, gastrointestinal AEs and genitourinary AEs, as well as events leading to trial product discontinuation and hypoglycaemic episodes