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Retatrutide E_max at GIPR 103%, GLP-1R 110%, GCGR 104% of native peptide peak (full agonist at all three at cAMP signaling per the conclusions section: "LY3437943 is a full agonist at the GCGR, GIPR, and GLP-1R in the functional assays")
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Storage and Handling Requirements To safeguard the complex structural integrity and prevent premature thermal or mechanical breakdown of the 30mg lyophilized cake, all vials must be stored long-term in a freezer environment at -20C, completely shielded from light and ambient moisture
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