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Proper needle selection enhances the absorption of the medication and minimizes patient discomfort, leading to better overall treatment outcomes
TG2 also catalyzes the incorporation of polyamines, including putrescine, spermidine, and spermine, into the glutamine residues of proteins to produce polyaminated proteins 3
doi: 10.1186/s13045-019-0720-y
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This distinction fundamentally shapes its pharmacokinetic profile, granting it properties (oral bioavailability, protease resistance, BBB penetration) that most neuropeptides lack
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