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10.1016/j.phrs.2019.104321 Pharmacol
Clin Toxicol 48:613 Du X, Edelstein D, Obici S, Higham N, Zou MH, Brownlee M (2006) Insulin resistance reduces arterial prostacyclin synthase and eNOS activities by increasing endothelial fatty acid oxidation
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They are not large enough to draw conclusions about using it as a treatment, nor to prove that L-theanine works
For patients who need significant weight loss, clinical performance makes the cost more justifiable than it first appears
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