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That said, some people who struggle with exercise find that GLP-1 therapy creates an indirect exercise benefit
SARS-CoV-2 spike protein S1 induces fibrin(ogen) resistant to fibrinolysis: implications for microclot formation in COVID-19
The rationale is that AOD 9604 preferentially targets adipose tissue, which might help shift the composition of weight loss more toward fat and away from lean mass
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Strange et al., 2000)
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![Physiologic effects of GLP-1 (adapted from Granata et al. [11])](https://www.researchgate.net/publication/359199250/figure/fig1/AS:11431281081130351@1661532031197/Physiologic-effects-of-GLP-1-adapted-from-Granata-et-al-11.png)
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