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Common adverse effects include gastrointestinal symptoms such as nausea, vomiting, diarrhea, and constipation, which typically diminish over time with continued use
Still, new or persistent symptoms deserve a medical check to rule out other causes
In particular, they have shown a reduction of major adverse cardiovascular events (MACE) in diabetic patients at high cardiovascular risk [23,24,25,26,27,28,29,30]
Elevated Chac2 increased intracellular GSH levels, enhanced GSH redox cycling, sustained ROS production, promoted NET formation, and increased inflammatory cytokine expression, collectively reinforcing the N1 inflammatory phenotype
Patients who stay on continuously tend to describe the same arc
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