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Missing data for the trial product estimand were handled through multiple imputation using the Markov Chain Monte Carlo method, assuming that non-adherent participants would have responded similarly to adherent participants within the same treatment arm

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Testing protocols include high-performance liquid chromatography (HPLC) for concentration and purity confirmation across all four peptide components, as well as mass spectrometry for molecular identity verification of GHK-Cu, BPC-157, KPV, and TB-500

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