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A prospective study involving 112 patients with severe obesity treated with semaglutide demonstrated that sex is a key predictor of therapeutic effect, with women showing significantly higher weight loss rates than men [78]

Glucagon suppression: Your pancreas releases a hormone called glucagon when you havent eaten in a while

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Similarly, in patients with obesity-related HFpEF (Heart Failure with Preserved Ejection Fraction), semaglutide produced substantial improvements in symptoms and exercise capacity [46]