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However, monotherapy with the Hh pathway inhibitor vismodegib did not show any significant antitumor activity in patients with ovarian cancer in a phase II clinical trial (NCT00739661) [189]
For mens performance or active-lifestyle formulas, the safer B2B pathway is to build around permitted ingredients, transparent labels, third-party contaminant screening, and compliant structure/function language such as supports energy metabolism or supports exercise recovery. Avoid disease-treatment claims, steroid-like positioning, and any implication that a formula contains or replaces prohibited research chemicals
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(Zhang et al., 2013a)
Theranostics 8:43724392
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