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Wellbutrin is a popular antidepressant that helps people manage depression, seasonal mood changes, and smoking cessation
This biopsy can be useful in distinguishing diffuse alopecia areata from early-stage scarring alopecia
Key molecular changes included the activation of tumor-suppressing pathways and the relocalization of the mTORC1 inhibitor DDIT4/REDD1, indicating a shift toward non-oxidative energy metabolism and reduce of tumor cell growth
The small number of subjects in this study is a caveat, and analysis of a larger number of subjects in the context of a clinical trial would be required to confirm these results and assess efficacy of the compounds