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On one hand, due to its low-carbohydrate content, the KD could decrease insulin levels, with a consequent increase in fat oxidation and reduced lipogenesis, 143 and induce a microbiome shift, with increased folate production and limited inflammatory and oxidative stress
Summary: Ozempic commonly causes changes in bowel movements, including both diarrhoea and constipation, due to its effects on gastric emptying and gut motility
For patients who find 12mg intolerable, stepping back to 8mg provides most of the benefit with better tolerability
When reactions do occur with semaglutide, they are predominantly mild erythema and pruritus
[2] The FDA declared the semaglutide injection shortage resolved in February 2025
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