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In fact, SGLT2-i induced osmotic diuresis and reduction in plasma volume potentially activate systemic RAAS, leading to an initial increase of renin levels in the first three-six months of treatment (53)
B12 injections are generally well-tolerated with mild injection site reactions, though rare hypersensitivity and hypokalaemia can occur, particularly when initiating treatment for severe deficiency
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The second path is a federated arrangement
doi: 10.3389/fmicb.2019.01386 21
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