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In addition, some putative effects of GLP-1RAs on cognitive and mental health symptoms may not require direct activity in the CNS, but rather be mediated by the actions that these medications express in the periphery across immune, endocrinemetabolic and gutbrain axis mechanisms (Fig
In accordance with the National Comprehensive Cancer Network guidelines, margins may be modified to accommodate individual anatomic or functional considerations
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Concerns have been raised regarding data quality, the lack of evidence-based case studies, and the absence of standardized definitions and categorizations of liver injuries, which may limit its reliability and applicability in clinical practice [69]
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