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SURMOUNT-1 enrolled adults with obesity or overweight without diabetes
The functions of amylin are complementary to insulin and to GLP-1 : Slows gastric emptying , similarly to GLP-1, but more strongly Suppresses glucagon , helps control postprandial glycemia Induces satiety , via the area postrema in the brainstem Regulates weight balance , long-term effect In type 2 diabetes amylin secretion deteriorates in parallel with insulin secretion , as the disease progresses, the -cells lose the ability to produce both hormones at once
The reality is that depression is one of the most prevalent dis-ease states in North America
How does amylin complement GLP-1 therapy, and why is that combination generating so much interest
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