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The conformational flexibility of TM11 appears to be linked with substrate recognition, with R471 (responsible for carnitine coordination) located near the midpoint of this helix, between the two segments that bend during the transition between inward-facing and occluded conformations

CL Answer Tablets I purchased are becoming "crumbly" after a few weeks and are easy to break

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Its also possible to feel no obvious sensation at the time of injection, apart from maybe a warmth if given IV