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The absorption spectra clearly suggest that TPE-DCV can react with GSH, Cys and Hcy through thiol-ene click reaction to form thioether (Figure S5)

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Moreover, the KEGG pathways associated with these core target genes included neutrophil extracellular trap formation, longevity regulating pathway, riboflavin metabolism, AGE-RAGE signaling pathway in diabetic complications, sphingolipid signaling pathway, p53 signaling pathway, HIF-1 signaling pathway (Fig

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