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Strikingly, substitution of proline at position 3 (P3A) abolished binding, yielding a KD = 56.7 (Fig
Glutamine has the ability to pass through the blood-brain barrier via a specialized transporter, so in theory, glutamine ingestion can increase levels of glutamine in the brain
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However, the Side effects of this supplement include headaches, dizziness, stomach upset, palpitations, and constipation
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