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When proliferation was inhibited by ATRA, changes in smooth muscle cell morphology also occurred

Therefore, this work serves as a preliminary study for the design of turn-on fluorescence strategy with improved performance on selectivity and sensitivity

Success requires careful peptide selection matching specific conditions, consistent long-term use (months to years for chronic diseases), proper dosing and administration, realistic benefit expectations (20-40% better preservation versus natural progression), financial commitment ($100-$500 monthly depending on protocols), patience through gradual timelines (3-6 months minimum assessing efficacy), and integration with proven conventional care

However, results of recent early-stage clinical trials indicate GKAs lose their efficacy after several months of use