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Jul 22 2022;27(15)doi:10.3390/molecules27154697
The absence of FDA approval means that use represents an off-label application requiring informed consent and medical judgment
218 Secondary mutations in BRAF, KRAS, NRAS, and MEK1/2 have been widely observed in patients treated with BRAF and MEK inhibitors, restoring ERK signaling and driving therapeutic failure
Cardiac-derived TGF-beta1 confers resistance to diet-induced obesity through the regulation of adipocyte size and function
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