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Core Mechanisms Recap: NNMT Inhibition: Prevents NAD depletion, supporting energy production and metabolic flexibility
AOD 9604 is supplied as a white lyophilized powder in a sealed research vial
Adjusting Frequency Based on Response The dose frequency might change based on how a patient responds
In white adipose tissue of obese, insulin-resistant and aged mammals, NNMT is dramatically upregulated and because it consumes both the universal methyl donor (SAM) and the NAD precursor (nicotinamide), its hyperactivity simultaneously depletes the cellular methylation reserve and the NAD-salvage pool [1,2]
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