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Some studies in women with PCOS showed reduced weight, BMI, and belly fat, so it may help women, too
Titration step values follow the REDEFINE Phase 3 protocol structure as reported by Novo Nordisk and the NEJM publications
There were two further phase IIa studies evaluating cotadutide with the first one showing that it reduced glucose levels in those with obesity and T2DM with the mechanism being greater insulin secretion and delayed gastric emptying [46]
Based on Lilly's approach with Zepbound (tirzepatide), which uses single-dose prefilled pens, retatrutide would likely be available in a similar pen format if approved
Chen Wei C, Peishan Z, Wenbin, et al
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