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MOTS-c is a mitochondrial-derived peptide (MDP) encoded within the mitochondrial genome that improves cellular energy metabolism, insulin sensitivity, and exercise capacity through AMPK activation and metabolic regulation
doi: 10.3389/fimmu.2021.720363 175 LushchakV
Jackson, MR
In addition to decreased CI, we found compromised CII activity in Gclc -deficient B cells
When the peptide binds to these receptors in fat tissue, it triggers a cascade that increases lipolytic enzymes, breaking down stored triglycerides into free fatty acids for energy use
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