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While semaglutide is a GLP-1 agonist, tirzepatide is known as a dual glucose-dependent insulinotropic polypeptide (GIP) receptor and glucagon-like peptide-1 (GLP-1) receptor agonist (GIP/GLP-1 agonist)
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There is a need for large-scale observational studies or head-to-head randomized trials that evaluate whether liraglutide, semaglutide, dulaglutide, and newer dual agonists such as tirzepatide offer different cancer risks or benefits due to their structural differences
Doctors offices are expending resources to get around barriers erected to limit the use of healthcare plan dollars on expensive medications for those the insurance plan and its managers determine do not need the drug, even when the doctors believe they do
Common side effects include: Nausea : This is the most common side effect of semaglutide
