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Evidence is strongest mechanistically and in wound/repair context not erase wrinkles in 14 days. ( MDPI ) Topical use is where it makes sense for therapists
At clinical doses under supervision, the most common side effects are mild nausea in the first week (typically resolves by day 7 to 10), injection site reactions (redness, minor swelling, localized soreness lasting 24 hours), and occasional transient fatigue or mild headache in the first few days
The chart below provides guidance for specific situations
GHK-Cu serum is a copper peptide formula that may support the appearance of skin firmness and a more even, refreshed-looking complexion over time
doi:10.1016/S0168-0102(00)00124-3
