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Grebe, A., Hoss, F
Given that NOX and NOS activity in neutrophils and macrophages depend upon G6PD-derived NADPH and reduced glutathione (GSH) (7), the role of G6PD and the PPP has been studied in these cell types, and roles for G6PD activity have been identified even beyond the oxidative burst
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Scientists use these documented pharmacokinetic characteristics to explore how tissues respond to oxidative stress and mechanical injury at a microscopic level
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