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This early worsening manifests as: Increased vitreous hemorrhage (bleeding into the eye) New or worsening macular edema (retinal swelling) Progression of proliferative changes Increased floaters from vitreous shifts Importantly, this appears to be a change early on (about three to six months) while taking the medication and should eventually improve the retinopathy and edema
Nagashima M, Watanabe T, Terasaki M, Tomoyasu M, Nohtomi K, Kim-Kaneyama J, et al
Combined with lower activity levels during recovery, these changes can contribute to excess calorie intake and weight gain
These changes support significant weight loss and enhance overall health, with benefits extending to heart health and diabetes management
They see big changes, losing around 15% of their body weight
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