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Tesamorelin in humans Two Phase 3 multicenter RCTs by Falutz and colleagues, published in the New England Journal of Medicine (2007) and the Journal of Acquired Immune Deficiency Syndromes (2010), enrolled HIV-positive adults with abdominal fat accumulation

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Before beginning therapy, lab tests are often performed to assess heavy metal levels, kidney function, and mineral status

Third, even the most elegantly engineered nutraceutical will fail if patients cannot or will not take it daily over months or years