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Moreover it is still important to note, that many patients treated in young age, that we follow-up today in cardiology/oncology departments, received treatment based on chemotherapy only and still need to be monitored for cardiotoxicity

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The requirement of two distinct glutathione interaction sites for the efficient reduction of GSSR by GSH explains the deviating properties and substrate preferences of glutaredoxin subfamilies as well as thioredoxins with implications for the design and optimization of artificial enzymes and inhibitors

Stopping too early limits healing potential