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Compromised glutamate transport in human glioma cells: reduction-mislocalization of sodium-dependent glutamate transporters and enhanced activity of cystine-glutamate exchange

It exists in both free and bound forms in the hypothalamus, limbic system, pituitary gland, and various peripheral organs, tissues, and fluids

Mitochondrial stress may increase free-radical production, while oxidative damage may further impair the electron transport chain

vi Low levels of glutathione have also been implicated in the cause and/or progression of cancer, inflammatory, immune, metabolic, and neurodegenerative diseases

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