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A., Sutradhar, L., Sarker, T

20.4% (vs 3.0% placebo) is the treatment-policy estimand intention-to-treat, everyone counted regardless of adherence and is the primary result published in NEJM

The tradeoff is that more water means fewer total days per vial (you cannot exceed the 28-day reconstituted shelf life) and a higher volume per injection

doi: 10.3389/fphar.2023.1267765 Received 27 July 2023 Accepted 09 October 2023 Published 13 November 2023 Volume 14 - 2023 Edited by Xinwang Yang, Kunming Medical University, China Reviewed by Yipeng Wang, Soochow University, China Lin Wei, Anhui Medical University, China Updates Copyright 2023 He, Wang and Qu

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