Epileptic patients, psychiatric inpatients, and cancer survivors frequently appear across the cases, indicating a need for personalized risk assessment in these groups
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Aberrant activation of signaling pathways and therapeutic implications Taken together, the aberrant activation of signaling pathways such as PI3K-AKT-mTOR, MAPK, NF-B, TGF-, Wnt/-catenin, JAK/STAT, Notch, Hippo-YAP/TAZ, and GAS6/AXL contributes extensively to therapy resistance across cancer types (Fig
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Bone deformation and osteopathy can also occur.[ref] There are three types of primary hyperoxaluria: [ref] Primary hyperoxaluria type 1 is caused by a mutation in the AGXT gene , which causes a deficiency in the bodys ability to metabolize glyoxylate into other compounds