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Pharmacists play a critical role in educating patients on the appropriate and safe use of GLP-1 agonists and also bear responsibility in reporting suspected serious adverse events with this new class of antidiabetic agents
These include: The severity of B12 deficiency The presence of underlying health conditions Genetic variations affecting B12 metabolism The duration of supplementation Knowing these factors helps tailor the dose to meet individual needs, ensuring the best results
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Therefore, there is a physiological basis for using the plasma BDNF as a functional surrogate for brain omega-3 FA levels, unlike the erythrocyte omega-3 FA levels, which are metabolically unrelated to the brain levels
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