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The importance of K10 P lipidation receives the support of our structure-activity relationship study where peptide 20 without K10 P lipidation reduced the receptor-mediated cAMP accumulation by 1,288-fold and 759-fold for GIPR and GCGR in the presence of 0.1% bovine serum albumin (BSA), respectively, but inappreciably influenced that of GLP-1R (Fig
Karger Medical and Scientific Publishers
Concentration response curves are expressed as AUC (020 min) for each concentration and normalized to the negative response observed by GLP-1 at 1 M
contributed to the clinical aspects of the study
The platinum agent introduces intra-strand crosslinks, which eventually lead to cell apoptosis in the absence of proper functioning of BRCA1/2
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