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To date, Phase 3 clinical trial data have also shown significant weight-loss outcomes, including up to 28.7% average body weight loss at 68 weeks in one obesity trial and 16.8% average weight loss at 40 weeks in adults with type 2 diabetes, with additional Phase 3 readouts still expected throughout 2026
However, Retatrutide is still under clinical investigation
JN: The Journal of Nutrition, 133 (12), 4135-4138
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Investigative efforts so far concerning enterotypes, such as alpha diversity, the Firmicutes-to-Bacteroidetes ratio, aim at the identification of an MDD-specific fecal signature (Valles-Colomer et al., 2019)
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