The FDA warns that both CJC-1295 and ipamorelin are risky for immunogenicity, potentially causing life-threatening outcomes such as anaphylaxis.25 26 Cardiovascular concerns: Specifically concerning CJC-1295, the FDA warns of the risk of increased heart rate and systemic vasodilatory reaction, including flushing, warmth, and transient hypotension.25 27 Cancer: With their ability to increase the rate of cellular replication, growth hormone secretagogues in general are unsafe for cancer survivors and people with an active cancer diagnosis.28 Secretagogue use may elevate their risk for recurrence or worsen their prognosis
These are the actions that make it popular for aging skin and wound healing
TB-500: 2 to 5mg injected twice weekly to maintain systemic levels
4 In adolescents, the risk of depression is higher among sexual minorities (gay, lesbian, bisexual, transgender), racial and ethnic minorities, and economically disadvantaged youth
Studies published before 2013, non-English language articles, and case reports were excluded