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Wegovy is initiated at a low dose (0.25 mg weekly) and gradually increased every 4 weeks through specific dose steps (0.25 mg 0.5 mg 1.0 mg 1.7 mg 2.4 mg)
[5] This rapid breakdown explains why therapeutic GLP-1 receptor agonists have been chemically modified to resist DPP-4 degradation, thereby extending their duration of action and clinical efficacy in managing diabetes and obesity
Most people start noticing subtle changes within a few days to weeks, though the timeline varies depending on your starting health status, lifestyle, and treatment frequency
This leads to feelings of fullness, reduced calorie intake, and decreased appetite
10.1016/j.molmet.2013.11.010 32
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