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PubMed pubmed.ncbi.nlm.nih.gov [66] Value of GLP-1 receptor agonists versus long-acting insulins for type 2 diabetes patients with and without established cardiovascular or chronic kidney diseases: A model-based cost-effectiveness analysis using real-world data ScienceDirect science/article/abs/pii/S0168822723001006 [67] Value of GLP-1 receptor agonists versus long-acting insulins for type 2 diabetes patients with and without established cardiovascular or chronic kidney diseases: A model-based cost-effectiveness analysis using real-world data ScienceDirect science/article/abs/pii/S0168822723001006 [68] Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes PubMed pubmed.ncbi.nlm.nih.gov [69] Efficacy and safety of GLP-1RAs for people with obesity: A systematic review based on RCT and Bayesian network meta-analysis ScienceDirect science/article/pii/S0753332224000313 [70] GLP-1 single, dual, and triple receptor agonists for treating type 2 diabetes and obesity: a narrative review ScienceDirect science/article/pii/S2589537024003614 [71] Emerging pharmacotherapies for obesity: A systematic review ScienceDirect science/article/pii/S0031699724000024 [72] Emerging pharmacotherapies for obesity: A systematic review ScienceDirect science/article/pii/S0031699724000024 [73] Emerging pharmacotherapies for obesity: A systematic review ScienceDirect science/article/pii/S0031699724000024 [74] Glucagon-like Receptor-1 agonists for obesity: Weight loss outcomes, tolerability, side effects, and risks ScienceDirect science/article/pii/S2667368124000299 [75] Tirzepatide once weekly for the treatment of obesity in people with type 2 diabetes (SURMOUNT-2): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial PubMed pubmed.ncbi.nlm.nih.gov [76] Tirzepatide once weekly for the treatment of obesity in people with type 2 diabetes (SURMOUNT-2): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial ScienceDirect [77] Tirzepatide once weekly for the treatment of obesity in people with type 2 diabetes (SURMOUNT-2): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial ScienceDirect [78] GLP-1 physiology informs the pharmacotherapy of obesity ScienceDirect [79] Tirzepatide once weekly for the treatment of obesity in people with type 2 diabetes (SURMOUNT-2): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial ScienceDirect [80] Glucagon-like Receptor-1 agonists for obesity: Weight loss outcomes, tolerability, side effects, and risks ScienceDirect [81] Glucagon-like Receptor-1 agonists for obesity: Weight loss outcomes, tolerability, side effects, and risks ScienceDirect [82] Glucagon-like Receptor-1 agonists for obesity: Weight loss outcomes, tolerability, side effects, and risks ScienceDirect [83] The promise of glucagon-like peptide 1 receptor agonists (GLP-1RA) for the treatment of obesity: a look at phase 2 and 3 pipelines PubMed pubmed.ncbi.nlm.nih.gov [84] The promise of glucagon-like peptide 1 receptor agonists (GLP-1RA) for the treatment of obesity: a look at phase 2 and 3 pipelines PubMed pubmed.ncbi.nlm.nih.gov [85] Emerging pharmacotherapies for obesity: A systematic review ScienceDirect [86] What is the pipeline for future medications for obesity

The reduction of cardiovascular disease does not decrease medical claims to the point where it is more financially beneficial to include the GLP-1s on the drug formularies because the claims resulting from the medication alone are higher than the claims related to cardiovascular treatments

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